Probiotic products / formulations enhance the intestinal homeostasis through enriching the intestinal microflora and promoting overall well being
Probiotics are gut-friendly microorganisms (bacteria and yeast) that confer various health benefits in the consumers, wherein they improve gut health and thus support in treating irritable bowel syndrome and antibiotic-induced diarrhea. Probiotic products comprise of approximately 1 to 10 billion colony forming units (CFUs) of viable microbial strains so as to generate the desired positive effect in the body, upon consumption.
These bacteria act as a potential barrier to the pathogenic bacteria in the body and regulates the immune cells in the body to fight the infection. Driven by the potential benefits of probiotics, there has been a surge in the research and development of novel probiotic products that can fulfil nutritional and / or clinical supplementation requirements. Through their metabolic and immunomodulatory actions, probiotics help prevent several health ailments, such as obesity, food allergies, diabetes, eczema and cancer. Notably, probiotics are now widely recognized as mainstream wellness products amongst the health-conscious population.
Live probiotic strains when formulated in dosage formats, such as tablets, capsules and powders, are considered as health supplements. These supplements can either be designed to target specific diseases or to maintain general health. Examples include nutritional supplements, specialty supplements and infant formula. In addition, various functional foods and beverages (containing probiotics) are consumed on a regular basis by the consumers, owing to its taste, texture and ease of incorporation in daily meals.
These include fermented foods, baked foods, chocolates, dried foods, fermented drinks, dairy and non-dairy products. Up lately, the pharmaceutical industry is extensively engaged in the development of advanced forms of probiotics, also known as next-generation probiotics. These probiotics can reduce oxidative stress, modulate the inflammatory pathways and prevent neurodegenerative diseases. Unlike traditional probiotics, these advanced products will have the potential in alleviating chronic human ailments, such as cancer through apoptosis induction, cytokine upregulation and exclusion of carcinogens.
The current market landscape features over 95 key probiotic companies that are engaged in offering probiotics. Several key companies (established as well as start-ups) in the probiotic domain offer various types of products, including probiotic foods, beverages, dietary supplements and infant formula. Notable examples of mid-sized probiotic companies based in Europe (in alphabetical order) include AB-BIOTICS, BioGaia, Enzymedica, Myprotein, PetLab and Zinereo Pharma. Interestingly, the end users of probiotic industry are children, infants, humans and animals. Various types of novel strains are being studied by the industry in order to identify its usage as a probiotic. These formulations can be used in foods, beverages, formulaes and supplements.
Most of the key probiotic companies were established pre-2000, depticting that the probiotics industry consists of some well-established players that have a strong customer base. Some examples of such probiotic companies include (in alphabetical order) adisseo, Bharat Biotech, Danone, IFF, Morinaga Milk, NowFoods, Tata, Yakult Honsha and Zipvit.
Majority of the key players (75%) offer probiotic dietary supplements; of these, more than 90% companies offer both nutritional as well as specialty supplements that support specific health conditions, such as mental, oral, bone, immune and women health. Apart from offering various types of probiotics for the human population, the key probiotic companies are also extensively engaged in offering probiotics for infants and children, whose microbiome is different and thus require different combinations of strains in the probiotic products.
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